Bones

Diet, lifestyle, and genetics play a vital role in defining the health of your bone structure. Regular sunlight exposure and a diet rich in Vitamin D can help support good bone health. However, certain gene variants can play a role in Vitamin D deficiency, which can lead to poor muscular and skeletal health.

Vitamin D / Predisposition to vitamin D deficiency

Vitamin D helps the body absorb the calcium from the food you eat. As calcium is the key mineral found in bones, it’s vital that your body has the ability to easily absorb calcium and strengthen the bones. Children who are Vitamin D deficient have a higher chance of developing rickets. For adults, Vitamin D deficiency has been linked to depression, erectile dysfunction, schizophrenia and heart disease.

GC rs7041 View details

Genome-wide association study of circulating vitamin D-binding protein. Moy et al. 2014

p-value 1x10^-246

participants 1380

GC rs2282679 View details

Genome-wide association study in 79,366 European-ancestry individuals informs the genetic architecture of 25-hydroxyvitamin D levels. Jiang et al. 2018

p-value 1x10^-187

participants 79366

GC rs705117 View details

Genome-wide association study of circulating vitamin D-binding protein. Moy et al. 2014

p-value 5x10^-91

participants 1380