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Our criteria of scientific evidence

  • research from 2013+
  • available clinical trials, those that started, followed, or ended.
  • research participants from 1000+
  • research from 2010+
  • research participants from 100+
  • p-value (10 ^ -50 - 10 ^ -800)


The health of the cardiovascular system depends on many factors, including cholesterol. Cholesterol metabolism is a complex process that involves dozens of genes and enzymes, so a defect in only one of the metabolic elements can disrupt the whole system.

LDL / Tendency to a high level of bad cholesterol

Lipoproteins of low density ( bad ) cholesterol affect the formation of atherosclerotic plaques.

HDL / Tendency to a low level of good cholesterol

High-density lipoproteins release cholesterol from the blood and reduce the risk of developing atherosclerotic plaques.

CETP rs3764261 View details
CETP rs17231506 View details
LIPC rs1532085 View details
ABCA1 rs1883025 View details
Homocysteine / Predisposition to homocysteine accumulation

A high level of homocysteine in the blood has a devastating effect on the blood vessels. The increase in its content may be genetically determined, particularly by mutations in the folate metabolism genes such as MTHFR and CUBN.

Caffeine / The rate of caffeine withdrawal

Whether or not caffeine is good for you depends on your metabolism. Those who process caffeine slowly have a greater risk of heart attack, while those who process caffeine quickly are safe - and may even protect themselves from certain cardiovascular disorders.

CYP1A2 rs762551 View details